In my latest article that I have just published I have put together a list of the 3 major signs of lupus and how these lupus disease symptoms can affect your body.  Lupus disease is known as the “great imitator” as many of its symptoms can suggest a different disease entirely.

I have been searching the most up-to-date information on the causes, prevention, cure, exercise, diet and many other important topics about lupus that I can find as I myself am a lupus patient.

I would really like to be able to help fellow lupus sufferers to alleviate their lupus symptoms and I think I have stumbled on something that is pure gold for people like myself.  It is based on research done by the 3 most renowned lupus experts in the world and they are teaching how to stop suffering the living hell of lupus through the gentle healing of natural alternatives.  I have been trying it for 2 weeks now and have seen amazing results, the most prevalent being that the pains in my joints have reduced greatly and my fever doesn’t spike so often now.  This natural lupus treatment has now offered me hope that remission from this disease really could be a reality.

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Studies revealed that 90% of people with lupus experience joint and/or muscle pain at some time during this illness.  Very often, the aching pain in joints and muscles can determine the patient believe he has a viral or flu-like illness, while other patients may have symptoms similar with those produced by arthritis. There exist also another category of patients with intense muscle inflammation, and they can also experience progressive weakness and loss of strength.

It must be said that muscle and joint pains are symptoms of lupus but usually it’s not the systemic lupus erythematosus responsible for them. They are more frequently caused by other illnesses.

Usually, the joint pain caused by lupus arthritis comes, may last for days or weeks, and then disappear, returning at a later time. It is known that the joints farthest from the trunk of the body are most frequently affected. Characteristic to lupus is stiffness and pain in the morning which improves during the day and can return later in the day when the person is tired, and also the fact that the pain is usually symmetrical, similar joints on both sides of the body are affected. It is good to know that even if a person has been diagnosed with lupus, there can appear pains that have nothing to do with this disease. For example, backaches or neck pains, a single, chronically painful are not provoked by lupus.

A fact that also should be remembered is that usually, lupus arthritis doesn’t cause deformities or destruction of the joints.  Best clues in order to determine if the pain is caused by the systemic lupus erythematosus is the pattern of joint pain and the setting in which it occurs.  There can be made X-rays of the painful joints and an examination of the synovial fluid within a swollen joint, to rule out other possible causes for the joint. It is known that if arthritis is the only symptom of lupus, diagnosis can be extremely difficult.  It is good to mention that sometimes, performing the anti-nuclear antibody test and the test for rheumatoid factor can be helpful.

For treating lupus arthritis, there are usually used non-steroidal, anti-inflammatory medications like ibuprofen, naproxen or aspirin. Usually, these medications have effect, but if this therapy is not effective, there can be added antimalarial drugs such as hydroxychloroquine.  In rare cases, if the joints remain swollen and painful despite other treatment, there begins the treatment with corticosteroids.  It is important that people learn joint protection procedures in order to rest the joints during flares of lupus arthritis, and another fact that must be known is that cytotoxic medications should not be used to treat only lupus arthritis.

It is known that the systemic lupus erythematosus can seriously damage the muscles, and as a result, there can appear muscle weakness and loss of strength. Inflamed muscles can be painful and tender to the touch, but the most common symptom that lupus myositis shows is muscle weakness. Usually, the muscles at he trunk of the body are affected , such as neck, pelvic girdle and thighs, shoulder girdle and upper arms.

There are some tests that can determine the severity of muscle involvement. These tests measure the level of some chemical enzymes in the blood. Normally, that enzymes are being concentrated within muscle fibers. They escape into the blood circulation when the muscle fibers are being damaged by inflammation.  There can also be made an electromyogram to determine the character of muscle damage in lupus myositis, and also biopsy may be performed in order to confirm the presence of inflammation and to identify how severe it is.

As a treatment, corticosteroids are used initially in high doses, to keep the inflammation under control, and then, after it subsides, it is gradually reduced. Most of the patients responde well to this treatment, but there are rare cases when it is necessary to add cytotoxic or immunosuppressive medications.A well directed exercise program should be started after the inflammation passed, in order to regain normal muscle strength and function.

It may happen when the patient is prescribed high doses of corticosteroids with or without cytotoxic agents to appear bone damage and muscle weakness. These complications in rare cases appear due to the effects of the medications alone, they usually come because of a combination of factors.  It was found that patients with systemic lupus erythematosus which took steroids for a long time can develop ischemic necrosis of bone. Altered blood flow to a portion of bone causes the death of that area, and as the bone repairs the area, a weakening of the bone occurs and a portion of the bone surface may collapse. Most affected are the hips, shoulders and knees.  The first symptom of ischemic necrosis is pain when the joints are being moved or bearing weight, and the pain can be felt even when the person is resting, at night, when the condition progresses.

Osteoporosis can also appear if a patient uses corticosteroids for a long time. Having osteoporosis means that the bone mass is decreased and a higher risk of bone fracture and compression of vertebrae in the spine appears. It is known that women are at a higher risk of developing osteoporosis and using calcium and vitamin D in addition to regular exercise may help prevent osteoporosis.

It is important to remember that people with lupus myositis should take a regular, well-designed exercise program in order to prevent muscle weakness.

Muscle and Joint Pain Causes

Causes for joint and muscle pain are varied. Systemic Lupus Erythematosus (SLE) is known to be one of the primary root causes. The pain is generally caused by soreness and inflammation of the joints and muscles which is characterized by [...]

Lupus Myositis

I think it could be lupus myositis. The tests will give us the answer. Anyway, if you have chronic pain (or know of someone who does), you’ll know that the last thing you need is some new manifestation when it’s tough enough dealing [...]

Prednisone side effects

I am in a flare with lupus myositis. My rheumatologist, who is very conservative re: prednisone has increased my dosage from 4mg to 15 mg daily. I am one of those folks who become almost manic on increased dosages.

Lupus – 4 Different Categories

About 10 percent of people with lupus also have symptoms characteristic of one or more additional connective tissue diseases such as rheumatoid arthritis, myositis, scleroderma and Sjogren’s syndrome.

Inclusion Body Myositis

Myositis is doctor speak for chronic skeletal muscle swelling or inflammation. Also medically voiced as inflammatory myopathy. The cause of this muscle [...]

More Research Labs for Antibodies

Since I had symptoms of myositis and a cousin who has Dermatomyositis, my blood was sent to a research lab that specialized in myositis antibodies at Oklahoma. Oklahoma also has a research lab that deals with Lupus and other autoimmune [...]

Author: Groshan Fabiola

For more resources about lupus rash please review this http://www.lupus-guide.com/ or even http://www.lupus-guide.com/symptoms-of-lupus.htm

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What Does A Lupus Rash Look Like?

The symptoms of lupus and its intensity are different from one case to another. It is an autoimmune disease, which occurs when the immune system abnormally releases its antinuclear antibodies and directs their attack against the organism’s own healthy tissues including, in some cases, even the DNA. The genetic material is thus altered itself by the aggressive action of the anti – DNA antibodies.

This organic chaos generates extremely damaging actions on the organs, causing kidney, heart or lung diseases, conditions of the nervous system – such as brain disease, skin affection like lupus rash, erythematous lesions, or musculoskeletal system problems (osteoporosis, arthritis).

Different patients usually experience different lupus symptoms. But the one that is constantly present in many cases is rash, in one of its two existing forms: systemic and discoid. It is the first sign of lupus and also the most persistent, unlike the others that appear and disappear over and over again.

This symptom affects the areas with increased exposure to the sunlight – the most dangerous enemy of a person with lupus – such as face, neck, shoulders and scalp. It is also possible for it to affect the chest, feet, palms and back and it usually comes with lesions of the skin. On the face, lupus generates the aspect of a red, burned skin and may also extend over the tissues that surround the nose and the mouth.

The systemic lupus erythematosus can be improved by the proper treatment. It doesn’t scar the skin, unless it is exposed to sunlight for large intervals.

The second form, the discoid lupus produces extended lesions in more than one body part. This form leads to the skin exfoliation, hyper – pigmentation and generates crusts. It usually leaves scars because its damaging actions get deeper in the skin layers. Serious scaring will remain on the skin in case the rush also involves papules, crust and intense scaling. Once it attacks the scalp, alopecia occurs (the loss of hair that may be temporary or permanent).

Another type of lupus rash is the subacute cutaneous form, which can be encountered in both systemic and discoid lupus. It affects the parts with the highest degree of solar exposure and takes the form of circular, scaly patches that have increasing surfaces of extension. It doesn’t completely disappear but it enters remission. The healing process involves hypo – pigmentation, without scarring. This type of rash can be successfully kept under control by the adequate medicines.

Solar exposure should be absolutely avoided in any type of lupus rash because it will seriously worsen the condition.

The question at the beginning of this article was “How long does Lupus rash last?” and the answer is that it varies from person to person.  There are so many varying severities of this symptoms of this disease that an exact time line cannot be given.  In general it can last from a few days to a few weeks, or in extreme cases it can even last months.  You can check with your doctor and they can help the healing process of the rash and get rid of it even quicker by the topical use of some creams.

Learning More About the Lupus Rash

The lupus panniculitis rash will appear on the skin as deep nodules. These are actually beneath the skin, residing in subcutaneous tissue. When such rashes heal, they will leave heavy scars. Another type of rash occurs in bullous lupus [...]

The Butterfly Rash

The lupus rash was first noticed and written about in the 1840s by a doctor in Vienna named Ferdinand von Hebra. He pronounced the butterfly shaped rash a symptom of lupus and blamed its angle on the stream of sunlight hitting the face.

4-step Treatment of Lupus

The treatment of lupus of course will depend upon the cause found in step 3. For many people, the lupus rash is aggravated by strong sunlight. In this case, patients are generally asked to look out for flare-ups and at the first sign [...]

Understanding Lupus and Staying Healthy

Discoid type lupus always affects the skin. It is characterized by a rash that appears on the face, neck, and scalp. Discoid lupus can be diagnosed by taking a biopsy of the rash and performing tests. The biopsy will show certain [...]

LUPUS

UV radiation has been shown to trigger the photosensitive lupus rash, but some evidence also suggests that UV light is capable of altering the structure of the DNA, leading to the creation of autoantibodies. Some researchers have found [...]

A Potential New Treatment for Severe Discoid Lupus

Discoid lupus is a form of lupus that affects the skin (cutaneous lupus). In most cases the discoid lupus rash appears on the face, neck, or scalp, though it can also show up on other areas of the skin. Severe discoid lupus may result [...]

By: Tobias Higgens -

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Learn what is lupus or about the symptoms of lupus and lupus treatment

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Systemic lupus erythematosus is a life-threatening chronic autoimmune disease. Although the mortality rate of patients with systemic lupus erythematosus has reduced in the last decades, the disease continues to raise serious problems to the affected persons. Research results reveal that around 2 million people in the United States suffer from systemic lupus erythematosus and almost 90 percent of patients are females.

The disease has the highest incidence in young women with ages between 18 and 30 years old. Asian, Hispanic and African American women are more exposed to developing systemic lupus erythematosus than white women. In Asian and African countries, the incidence of the disease in women is known to be a lot higher than in the United States. Furthermore, Asian and African American women seem to develop more serious forms of the disease. Systemic lupus erythematosus is also common in infants, very young children and elderly people.

Modern medicine is unable to establish the actual causes of systemic lupus erythematosus. It is believed that there are multiple inter-related factors that determine the occurrence of the disease: genetic anomalies, environmental factors (prolonged medical treatments with strong antibiotics) and hormonal factors (since the disease is predominant in women, estrogen seems to be involved in the occurrence of the disease).

Systemic lupus erythematosus can affect different parts of the body, sometimes even causing permanent damage. Lupus involves dysfunctions or hyperactivity of the immune system, which begins to attack healthy blood cells and genetic material. Instead of protecting the body from infectious agents and malign organisms, the immune system produces antinuclear antibodies that attack the DNA (deoxyribonucleic acid). Systemic lupus erythematosus can affect the cardiovascular system, the lungs, the gastrointestinal tract, the kidneys, the nervous system and brain, the musculoskeletal system or skin.

People with systemic lupus erythematosus commonly suffer from affections of the joints, heart disease, pulmonary disease or skin diseases. Considering the multitude of generated symptoms, people with systemic lupus erythematosus require various medical treatments for each particular disorder.

The treatment for systemic lupus erythematosus is mainly targeted at reducing the damage caused by the dysfunctional immune system to the body. Immunosuppressive medications are very common in the treatment for lupus. Although they can generate pronounced side-effect, corticosteroids are often used in the treatment of systemic lupus erythemaosus. However, doctors are trying to minimize the use of harmful drugs such as azathioprine (Imuran) and cyclophosphamide (Cytoxan).

The chronic character of systemic lupus erythematosus determines the recurrence of its symptoms. The disease has an unpredictable evolution pattern, alternating between periods of remission and periods of aggravation. Even if systemic lupus erythematosus is inactive, the patients still require permanent monitoring and frequent physical examination. Also, due to prolonged treatments with immunosuppressive medications, patients with systemic lupus erythematosus are very susceptible to infections. People with systemic lupus erythematosus need to take steps in preventing the occurrence of infectious diseases, as on the background of a compromised immune system, even a common flu can generate exacerbated symptoms.

By: Groshan Fabiola

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So if you want to find more about Lupus or more details about systemic lupus please follow this link www.lupus-guide.com

Information Lupus

Seems that the symptoms of the systemic lupus erythematosus are the same in men and women too, at least at the beginning of the disease.

Lupus Medications: What Are My Options?

Lupus medications are an important aspect of treatment for many patients with systemic lupus erythematosus. An array of medications and drug therapy options are now available to treat lupus.

Rheumatic Disease

Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by the universal presence of autoantibodies and a wide range of clinical manifestations.

Lupus/SLE

Wonder what causes lupus? Lupus, an autoimmune disease, happens when the immune system attacks its tissues, causing inflammation, swelling, pain, and damage. Lupus symptoms vary, and early lupus symptoms include fatigue, joint pain, …

Systemic Lupus Erythematosus

Drug-Induced Lupus. vDrug-Induced Lupus Erythematosus: Is a syndrome that resembles SLE and is associated with symptoms such as fever, malaise, arthritis, serositis, and rash. Has a less severe and less dramatic clinical presentation [...]

My symptoms + Lupus in Family…

My symptoms + Lupus in Family… Lupus. … My uncle and my sister both have SLE. My sister died several years ago due to SLE complications. An ideas what I should do or kind of Doctor I should see.

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Studies revealed that about a third of patients that have systemic lupus erythematosus can develop a kidney disease called lupus nephritis or lupus glomerulonephritis.Lupus nephritis usually shows very few signs. It doesn’t cause pain or burning during urination and also it does not produce pain in the abdomen or back.The first symptom the patient with lupus nephritis usually experiences is puffiness in the legs, ankles or fingers. This happens because the loss of protein in the urine may lead to fluid retention with weight gain and swelling.

Sometimes the fact that a patient has lupus nephritis is discovered only after urine studies are made. It is very possible that if there is made another urine test, the urine abnormalities to disappear. But there are patients in which the abnormal findings on urine studies persist or can become even worse in time. This kind of patients require more studies to determine the best treatment to control the disease, because there appears the risk for loss of kidney function.
It is important to know that patients having lupus can experience some symptoms that confuse them and think they have lupus nephritis. For example infections of the urinary tract with burning on urination, or medications used in lupus treatment may produce signs that can start the confusion.There are some tests that can be done in order to find out if a patient has lupus nephritis.

Urinalysis is the most used and the most simple test to do. A urine sample is studied to find out if there is protein and blood cells which are not normally found in the urine.If in the urine sample there are found red blood cells, white blood cells, casts(excretion in the urine of protein or blood cells that collect within the tubules of the kidney), or there is discovered the presence of protein, there exists the possibility of lupus nephritis, and further tests are necessary.Sometimes, it is done a urine collection over a period of 24 hours to measure the kidneys’ ability to filter waste products.

Blood studies can also be performed, and we can mention the blood urea nitrogen and serum creatinine. These are tests that are made to find out if waste products are being removed properly by the kidney and are not building up in the blood.By measuring the serum albumin, it can be determined if there is a low protein level in the blood, and chemistry studies such as the serum sodium, potassium, and bicarbonate determine the imbalances of salt and water in the blood.There can be also made blood tests in order to determine if there are abnormalities of the immune system.

An intravenous sonogram or pyelogram can be made to determine the size and shape of the kidneys. Usually this test takes place before a kidney biopsy.The kidney biopsy takes place in order to confirm the diagnosis of lupus nephritis. It is made by inserting a needle through the skin of the back and removing a tiny piece of the kidney.Then, the small part taken from the kidney is analyzed under the microscope in order to determine how much inflammation or permanent damage is present within the kidney.

There are four most common types of nephritis: focal or diffuse proliferative nephritis, mesangial nephritis and membranous nephritis.

The treatment for lupus nephritis must be individualized, because there are different patients having different needs. It is important that all factors that appear to be taken in consideration when deciding the treatment.General principles of medical management of kidney disease include anti-hypertensive drugs to control increased blood pressure, diuretic agents to help eliminate excess fluid, changes in the diet to control the intake of salt, proteins and calories. These are very important in lupus nephritis.

Corticosteroids are often used to treat lupus nephritis. We can mention here prednisolone, prednisone and methylprednisolone. There still are some unanswered question about how corticosteroids work and how they may be most effectively used. Usual, high doses of corticosteroids are given until there appears improvement in the lupus nephritis. Then , the dose is reduced, but there is done a careful observation by the physician to make sure that the nephritis doesn’t get worse.If corticosteroids are given for long periods, there can appear side effects, like easy bruising, increase in appetite and fluid retention with weight gain, cataracts, thinning of the hair, an increase in the risk of infection, diabetes and other.

When patients do not respond at corticosteroid treatment, they are given Cytotoxic or immunosuppressive drugs such as azathioprine or cyclophosphamide. The effect of these drugs is to block the function of the immune system.As a result, further damage to the kidneys is prevented. However, even if these drugs may be beneficial, they can also bring serious complications.

Although there is appropriate treatment, there are patients that develop progressive loss of kidney function and renal failure. This requires the use of artificial dialysis, and that can be done by hemodialysis or peritoneal dialysis.Also, it can be made a kidney transplantation, and it is known that this has been very successful in patients with renal failure from lupus nephritis.

Over the years, science advanced in the understanding of what causes lupus nephritis, and there were made improvements in ways to treat patients.

By: Groshan Fabiola

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For more resources about discoid lupus please review this www.lupus-guide.com/lupus-treatment.htm or even www.lupus-guide.com/discoid-lupus.htm

Acute renal failure in paediatric systemic lupus erythematosus

Efficacy and safety of treatment regimens were compared. Methods. A total of 249 pSLE patients were diagnosed and prospectively followed at a single centre between July 1973 and July 2003; 127 children (51%) had lupus nephritis.

Drugs Comparable for Adolescent Lupus Nephritis

All patients met ACR criteria for SLE and had active or active/chronic Class III, IV, or V lupus nephritis, which had been confirmed by kidney biopsy within six months of randomization.

Lupus Nephritis and Its Medications

It is predictable that roughly one-third of people with lupus will build up nephritis that needs medical check up and treatment. Lupus nephritis is a significant and potentially critical symptom of lupus.

Update on the treatment of lupus nephritis

Therapy of lupus nephritis can be divided into an induction phase and a maintenance phase. Initial treatment is usually more aggressive and aims at inducing remission of nephritis while maintenance therapy is needed to prevent renal [...]

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Lupus can be extremely difficult to diagnose in the early stages due to its creepy onset. The early symptoms of lupus vary individually as the first symptoms depend upon the organ affected.

Getting hold of a good physician who may either be a rheumatologist or a dermatologist is of utmost importance for not being called hypochondriacs and being treated wrongly.

What is lupus?
Lupus also known as SLE or Systemic Lupus Erythematosus is an auto-immune rheumatic disease that can affect all the systems of the body. The disease affects women more often than men and children.

Lupus Disease
The early symptoms of lupus are mild enough to brush aside as they do not affect your daily life. However the collective discomfort caused by these meek signs is worth considering until you find a convincing cause for it.

Types of Lupus
Discoid Lupus, Systemic Lupus and Drug-induced lupus are the different types of lupus and they affect the skin, multiple body organs or both respectively. When a drug causes the symptoms, they are totally reversible.

Early symptoms of SLE

• Fatigue
• Malaise
• Sudden weight loss or gain
• Hair loss
• Easy bruising
• Facial Rash: It maybe the first symptoms of SLE and also persistent, unlike the rest of the signs that tend to flare up and subside. It ranges from mild blush to scaling and itching.
• Photosensitivity – The sun-exposed parts of the face and neck develop redness or rashes. Skin sensitive to UVA-UVB sun rays as well as the UV rays from bulbs and lamps.
• Blue, red or white coloration at the finger tips on exposure to cold climate or cold water.Such type of Raynaud’s phenomenon is also seen at other sites like tip of nose, ears and feet.

Additional symptoms affecting the various organs

• Fever
• Mouth ulcers
• Joint pain and swelling
• Stiffness in joints and muscle pain
• Butterfly skin rash on the cheeks and nose
• Chest pain or breathing difficulty
• Neurological symptoms like confusion and epileptic attack
• Depression
• Signs of kidney disease
• Blood clotting tendency
• Miscarriages
• Low platelet count
• Anemia

SLE imitates many other illnesses that need to be ruled out. The absence of positive laboratory results in early phase of lupus makes it all the more difficult to diagnose. Once diagnosed a treatment regimen needs to be meticulously followed under strict supervision to make the disease self-limiting. The fatality caused by lupus has significantly decreased in the last 25 years mainly due to diagnosis of disease in the early stages, effective laboratory facilities and drug research.

The prognosis has greatly increased with recent advances in the field of medicine, and some patients can go into remission. Also one needs to keep a watch on the signs of relapse as SLE tends to show flare ups just like arthritis.

By Dr. Meenaz M
Published: 1/1/2008

Systemic Lupus Erythematosus

Systemic lupus erythematosus, OR SLE, is an autoimmune disorder that affects many parts of the body. An autoimmune disorder is a condition in which the body creates antibodies against its own tissues. What is going on in the body?

Drug-Induced Lupus Erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disorder that affects many parts of the body. An autoimmune disorder is a condition in which the body creates antibodies against its own tissues.

Lupus Support Group in Winchester, VA…..need members…anyone …
Since the closest support group is in Washington DC I decided to set up a Lupus Support Group in Winchester, VA. I have been out of the loop with my fellow lupies and it is time to reunite:))

Lupus affects brain ‘earlier than thought’
The brain is affected very early in the progression of systematic lupus erythematosus (SLE), new research in the Journal of Rheumatology has found.

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