Dr. Diane M. Hoss, MD discusses Discoid Lupus Erythematosus – Clinical. See more at www.dermnet.com PLEASE RATE AND COMMENT!!! Discoid lupus erythematosus (DLE) is a form of chronic cutaneous lupus erythematosus characterized by hyperkeratotic inflammatory plaques which eventuate into areas of scarring. Only 5% of DLE patients go on to develop systemic lupus erythematosus (SLE). However, 25% of SLE patients have discoid lesions. DLE lesions occur most commonly on the head and neck. Patients with generalized DLE lesions involving the skin above and below the neck are more likely to develop SLE. Scalp lesions occur in 60% of DLE patients and usually result in scarring alopecia. DLE lesions are red to purple plaques with hyperkeratotic scale. There are follicular hyperkeratotic plugs causing a carpet tack appearance as they project from the undersurface of the scale when it is removed from advanced lesions. The dyspigmentation of older lesions often presents as central hypopigmentation and peripheral hyperpigmentation. Patients may have scalp lesions only or may have concomitant lesions on the face, neck, and especially the external ears.
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Dr. Diane M. Hoss, MD discusses Discoid Lupus Erythematosus – Histology. See more at www.dermnet.com PLEASE RATE AND COMMENT!!! DLE lesions demonstrate interface changes at the dermal-epidermal junction and the basement membrane zone region of follicular epithelium. Necrotic keratinocytes and lymphocytic inflammation are present in these interface areas. There is superficial and deep inflammation consisting of lymphocytes and plasma cells. The follicles are eventually replaced by fibrosis and there may be interfollicular dermal scarring. Increased dermal mucin is often present. Direct immunofluorescence may show linear granular deposits of C3 and IgG at the dermal-epidermal junction and in the basement membrane zone area of follicular infundibula.
How to handle lupus treatments like Prednisone in thishome health video. Expert: Heather Kamins Bio: Heather Kamins has a Master of Fine Arts in creative writing from Mills College in Oakland, Calif. She has taught and tutored English composition at Mills, as well as at the College of Alameda. Filmmaker: Dimitri LaBarge
How to find the right doctor for lupus treatments in thishome health video. Expert: Heather Kamins Bio: Heather Kamins has a Master of Fine Arts in creative writing from Mills College in Oakland, Calif. She has taught and tutored English composition at Mills, as well as at the College of Alameda. Filmmaker: Dimitri LaBarge
How teens live with lupus symptoms in this home health video. Expert: Heather Kamins Bio: Heather Kamins has a Master of Fine Arts in creative writing from Mills College in Oakland, Calif. She has taught and tutored English composition at Mills, as well as at the College of Alameda. Filmmaker: Dimitri LaBarge
A description of the autoimmune disease Lupus Erythematosus.
How to exercise and live with lupus in this home health video. Expert: Heather Kamins Bio: Heather Kamins has a Master of Fine Arts in creative writing from Mills College in Oakland, Calif. She has taught and tutored English composition at Mills, as well as at the College of Alameda. Filmmaker: Dimitri LaBarge
How to eat right and live with lupus in this home health video. Expert: Heather Kamins Bio: Heather Kamins has a Master of Fine Arts in creative writing from Mills College in Oakland, Calif. She has taught and tutored English composition at Mills, as well as at the College of Alameda. Filmmaker: Dimitri LaBarge
How to live with lupus symptoms like fatigue in this home health video. Expert: Heather Kamins Bio: Heather Kamins has a Master of Fine Arts in creative writing from Mills College in Oakland, Calif. She has taught and tutored English composition at Mills, as well as at the College of Alameda. Filmmaker: Dimitri LaBarge
How to live with lupus symptoms like arthritis in this home health video. Expert: Heather Kamins Bio: Heather Kamins has a Master of Fine Arts in creative writing from Mills College in Oakland, Calif. She has taught and tutored English composition at Mills, as well as at the College of Alameda. Filmmaker: Dimitri LaBarge
